They not only break down peroxides but also transmit their oxidative effect in a controlled manner to other proteins, thus transmitting cellular signals.
Actively growing tumors have a high demand for oxygen and nutrients.
Therefore, they stimulate the growth of blood vessels. If tumor-associated angiogenesis is suppressed, this may limit tumor growth.
This underscores the role of metabolism in heart failure.
In addition, these findings are relevant for the use of certain anticancer drugs.
Kristian Pajtler, a pediatric oncologist from the "Hopp Children's Cancer Center at the NCT Heidelberg" (Ki TZ), received the 2018 CERN Scientific Fellowship Award with a monetary prize of 100,000 US dollars.
Pajtler has been awarded the distinction for his work on ependymoma, a rare type of brain cancer.
In certain blood cancer cells, this cluster has been altered, which affects Myc activity and thereby accelerates cancer growth and affects how the cancer responds to chemotherapy.
This cluster of enhancers might therefore be a suitable target in the treatment of blood cancer.
Communicative peroxidases Reactive oxygen species (ROS) are oxidizing molecules that are produced, for example, in cellular respiration and in inflammatory processes.